Document Detail

Diagnosis of Toxoplasma gondii by ELISA and PCR in mothers and their infants.
MedLine Citation:
PMID:  19795769     Owner:  NLM     Status:  MEDLINE    
Congenital Toxoplasma gondii infection may lead to abortion, stillbirth, neonatal death as well as severe congenital toxoplasmosis in the newborn infants. No doubt, early and proper diagnosis of infection pregnant women or her baby pave the way to effective treatment and minimize complications. In this study; the PCR and ELISA-IgM were used to diagnose active toxoplasmosis. The results revealed that PCR detected very recently infection (23/70 subjects) than ELISA-IgM (18/70 ones). However, the use of both ELISA-IgM and PCR together improved the diagnostic sensitivity and specificity.
Ibraheim M Nagaty; Khadra M Ibrahim; Ahmad H Abdel-Tawab; Alaa-Eldin A Hassan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Egyptian Society of Parasitology     Volume:  39     ISSN:  1110-0583     ISO Abbreviation:  J Egypt Soc Parasitol     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-10-02     Completed Date:  2009-11-03     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  8102141     Medline TA:  J Egypt Soc Parasitol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  625-32     Citation Subset:  IM    
Department of Parasitology, Faculty of Medicine, Universities of Benha, Benha, Egypt.
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MeSH Terms
Antibodies, Protozoan / blood
Enzyme-Linked Immunosorbent Assay*
Immunoglobulin M / blood
Infant, Newborn
Polymerase Chain Reaction*
Pregnancy Complications, Parasitic / diagnosis*,  epidemiology
Sensitivity and Specificity
Toxoplasma / immunology,  isolation & purification
Toxoplasmosis / diagnosis*,  epidemiology,  transmission
Toxoplasmosis, Congenital / diagnosis*,  epidemiology
Reg. No./Substance:
0/Antibodies, Protozoan; 0/Immunoglobulin M

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