Document Detail


Diagnosing acute retrobulbar neuritis by vitreous fluorophotometry.
MedLine Citation:
PMID:  7246699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied six patients with acute retrobulbar neuritis (including two with definite multiple sclerosis) during acute episodes and in convalescence, clinically and with fluorescein angiography and vitreous fluorophotometry. We compared vitreous fluorophotometric readings with visual-evoked responses. In seven of ten eyes with abnormal visual-evoked responses, there was an acute increase in posterior vitreous fluorophotometric readings. Vitreous fluorophotometry may be useful as objective evidence of (1) acute retrobulbar neuritis, (2) involvement of the asymptomatic eye in acute retrobulbar neuritis, (3) the duration of neuritic inflammation in acute retrobulbar neuritis, (4) a recurrence of acute retrobulbar neuritis, (5) alterations in the blood-ocular barrier in patients with acute retrobulbar neuritis in multiple sclerosis, and (6) the effects of corticosteroids and other therapeutic agents in the treatment of acute retrobulbar neuritis.
Authors:
L S Braude; J G Cunha-Vaz; M F Goldberg; M Frenkel; J R Hughes
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  91     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1981 Jun 
Date Detail:
Created Date:  1981-08-20     Completed Date:  1981-08-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  764-73     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Evoked Potentials
Female
Fluorescein Angiography
Humans
Male
Middle Aged
Optic Neuritis / diagnosis*
Photic Stimulation
Photometry / methods
Vitreous Body / analysis*
Grant Support
ID/Acronym/Agency:
EY01792/EY/NEI NIH HHS; EY03106/EY/NEI NIH HHS; EY7038/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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