| Diabetic ketoacidosis preceding thrombocytopenia associated multiple organ failure in a child. | |
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MedLine Citation:
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PMID: 21206100 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONTEXT: Thrombocytopenia associated multiple organ failure is a rare but increasingly recognized condition in children. Diabetic ketoacidosis preceding thrombocytopenia associated multiple organ failure is previously unreported in pediatric patients. CASE REPORT: A 12-year-old female presented with diabetic ketoacidosis along with acute pancreatitis. She further developed thrombocytopenia and renal failure over the next two days. Although hemolytic uremic syndrome/thrombotic thrombocytopenic purpura spectrum was considered, the clinical picture seemed most consistent with thrombocytopenia associated multiple organ failure. The patient was treated with serial therapeutic plasma exchanges and made a complete recovery. CONCLUSION: A high index of suspicion of thrombocytopenia associated multiple organ failure is required in patients with diabetic ketoacidosis or pancreatitis who present with thrombocytopenia and renal failure. Plasma exchange is a life-saving intervention in such cases. |
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Authors:
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Kamakshya P Patra; L Keith Scott |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2011-01-05 |
Journal Detail:
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Title: JOP : Journal of the pancreas Volume: 12 ISSN: 1590-8577 ISO Abbreviation: JOP Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-05 Completed Date: 2011-04-28 Revised Date: 2011-10-18 |
Medline Journal Info:
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Nlm Unique ID: 101091810 Medline TA: JOP Country: Italy |
Other Details:
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Languages: eng Pagination: 40-3 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, LA, USA. kpeds2008@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Child Diabetic Ketoacidosis / complications* Diagnosis, Differential Female Hemolytic-Uremic Syndrome / diagnosis Humans Multiple Organ Failure / diagnosis*, etiology*, therapy Pancreatitis / complications Plasma Exchange Purpura, Thrombocytopenic / diagnosis Thrombocytopenia / diagnosis*, etiology*, therapy Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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