Document Detail


Diabetes and the risk of heart failure.
MedLine Citation:
PMID:  22108732     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Prevalence of diabetes and heart failure are increasing exponentially worldwide. Diabetes is well-known to increase the risk of heart failure independent of other traditional risk factors and ischemia. Current evidence indicates the presence of several biochemical and molecular changes associated with diabetes that lead to diastolic dysfunction or American Heart Association stage B heart failure. Some, if not all, changes may also predate the development of frank diabetes. In this review, the authors present some of the epidemiologic evidence and a brief description of major mechanistic pathways that favor the development of heart failure in prediabetic and diabetic states.
Authors:
Ravi Dhingra; Ramachandran S Vasan
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2011-10-13
Journal Detail:
Title:  Heart failure clinics     Volume:  8     ISSN:  1551-7136     ISO Abbreviation:  Heart Fail Clin     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-11-23     Completed Date:  2012-03-27     Revised Date:  2013-02-20    
Medline Journal Info:
Nlm Unique ID:  101231934     Medline TA:  Heart Fail Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  125-33     Citation Subset:  IM    
Copyright Information:
2012 Elsevier Inc. All rights reserved.
Affiliation:
Section of Cardiology, Heart and Vascular Center, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA.
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MeSH Terms
Descriptor/Qualifier:
Diabetes Complications / complications*,  epidemiology
Disease Progression
Heart Failure / epidemiology,  etiology*
Humans
Incidence
Risk Factors
United States / epidemiology
Grant Support
ID/Acronym/Agency:
N01 25195//PHS HHS; N01 HC025195/HC/NHLBI NIH HHS
Comments/Corrections

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