Document Detail


Diabetes and rheumatic diseases.
MedLine Citation:
PMID:  19077719     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: This review summarizes recent advances in the field of diabetes and rheumatic disease. These conditions exert a significant healthcare burden on our society and much remains to be learned regarding their pathophysiology and treatment. RECENT FINDINGS: We summarize new insights into diabetes and its association with osteoarthritis, rheumatoid arthritis, carpal tunnel syndrome, osteoporosis, diffuse idiopathic skeletal hyperostosis, crystalline arthropathy, neuropathic arthropathy, and tendinopathy. Diabetes has major effects on connective tissues, which have significant impact on both the development and outcome of these diseases of cartilage, bone, ligament, and tendon. An improved understanding of the mechanisms through which diabetes alters connective tissue metabolism should lead to better preventive and therapeutic interventions. SUMMARY: Incremental progress has been made in understanding the interactions between diabetes and common musculoskeletal syndromes. Although this review highlights exciting areas of future interest, more work in this field is certainly warranted.
Authors:
Todd W Burner; Ann K Rosenthal
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in rheumatology     Volume:  21     ISSN:  1531-6963     ISO Abbreviation:  Curr Opin Rheumatol     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-03-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9000851     Medline TA:  Curr Opin Rheumatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  50-4     Citation Subset:  IM    
Affiliation:
Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, Zablocki VA Medical Center, Milwaukee, Wisconsin 53295-1000, USA.
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MeSH Terms
Descriptor/Qualifier:
Arthritis / immunology,  metabolism,  physiopathology*
Cartilage / immunology,  metabolism,  physiopathology
Connective Tissue / immunology,  metabolism,  physiopathology*
Diabetes Complications / immunology,  metabolism,  physiopathology*
Gout / immunology,  metabolism,  physiopathology
Humans
Hyperostosis / immunology,  metabolism,  physiopathology
Rheumatic Diseases / immunology,  metabolism,  physiopathology*
Tendinopathy / immunology,  metabolism,  physiopathology
Tendons / immunology,  metabolism,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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