| Diabetes mellitusin a cohort of patients with acromegaly. | |
| | |
MedLine Citation:
|
PMID: 22231975 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVES: To evaluate the presence of diabetes mellitus (DM) in a cohort of patients with acromegaly. METHODS: This was a cross sectional study. RESULTS: Fifty-eight acromegalic patients were assessed. Only 29% met the criteria for cure, and 27% had the disease controlled. Twenty-two had DM; HbA1c was equal to 7.34 ± 2.2%. Most of the diabetic patients (18 out of 22, 82%) did not meet criteria for cure. They were more often hypertensive [16/22 (73%) vs. 17/36 (46%), p = 0.04], and used statins more frequently [14/22 (64%) vs. 8/36 (21%), p = 0.004]. After regression analysis, hypertension was associated with diabetes [odds ratio (OR): 9.28 (95% CI: 1.59 - 54.00), p = 0.01], and cured/ controlled acromegaly was associated with protection against the presence of diabetes [OR: 0.17 (95% CI: 0.03 - 0.78), p = 0.02]. CONCLUSIONS: The presence of DM was associated with active acromegaly and presence of hypertension. However, absolute levels of GH and IGF-1 did not differ between patients with and without diabetes. |
| | |
Authors:
|
Ticiana Costa Rodrigues; Fabiola Costenaro; Daniela Fedrizzi; Marcelle D Oliveira; Paula B de Lima; Vitor Boschi; Mauro Antônio Czepielewski |
Related Documents
:
|
2387195 - Accuracy of reported family history of diabetes mellitus. results from san luis valley ... 12050325 - Sequential (201)tl imaging and dobutamine echocardiography to enhance accuracy of predi... 20618275 - Quantifying the duration of pre-diabetes. 8092205 - Impact of time since last meal on the gestational glucose challenge test. the toronto t... 7589765 - Relationship between cardiosympathetic neuropathy and diabetic somatic neuropathy in pa... 18650995 - Pharmacological preconditioning with diazoxide slows energy metabolism during sustained... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Arquivos brasileiros de endocrinologia e metabologia Volume: 55 ISSN: 1677-9487 ISO Abbreviation: Arq Bras Endocrinol Metabol Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2012-01-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0403437 Medline TA: Arq Bras Endocrinol Metabol Country: Brazil |
Other Details:
|
Languages: eng Pagination: 714-9 Citation Subset: IM |
Affiliation:
|
Programa de Pós-Graduação em Ciências Médicas - Endocrinologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [Analysis of factors associated with changes in the oral glucose tolerance test, regardless of the v...
Next Document: Diabetes mellitus and spinal epidural abscess: clinical or surgical treatment?