Document Detail

Diabetes mellitus and the risk of preterm birth with regard to the risk of spontaneous preterm birth.
MedLine Citation:
PMID:  20059440     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: It is internationally agreed that diabetes mellitus (DM) is associated with increased maternal and fetal morbidity and long-term complications. To avoid these complications, it is often necessary to induce birth before term. The impact of DM on spontaneous preterm birth (spontaneous labor, preterm premature rupture of membranes and/or cervical incompetence resulting in delivery before the completion of 37 gestation weeks) is still unexplained. Preterm birth accounts for the most neonatal deaths and infant morbidities, and therefore it still remains one of the biggest challenges in obstetrics.
OBJECTIVE: Our study determined if there is an increasing tendency towards spontaneous preterm birth in mothers with gestational and preexisting DM.
METHODS: In this retrospective cohort study, 187 pregnant women with gestational DM and preexisting DM were compared to a randomized control group consisting of 192 normoglycemic women concerning gestational age and perinatal outcome. Data were collected by the Medical University of Vienna. Multiple pregnancies and women with severe maternal diseases, such as preeclampsia, were excluded.
RESULTS: Women with DM tended significantly more often to preterm births (P = 0.002). A significant difference in the incidence of spontaneous preterm birth was found (P = 0.047).
CONCLUSION: DM affects the length of gestation and incidence of spontaneous preterm birth.
Katharina Köck; Florian Köck; Katharina Klein; Dagmar Bancher-Todesca; Hanns Helmer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  23     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-19     Completed Date:  2010-12-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1004-8     Citation Subset:  IM    
Department of Obstetrics and Feto-Maternal Medicine, University of Vienna General Hospital, Austria.
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MeSH Terms
Case-Control Studies
Cohort Studies
Diabetes, Gestational / epidemiology*
Fetal Membranes, Premature Rupture / epidemiology,  etiology
Gestational Age
Infant, Newborn
Obstetric Labor, Premature / epidemiology,  etiology
Pregnancy in Diabetics / epidemiology*
Pregnancy, Multiple
Premature Birth / epidemiology*,  etiology*
Retrospective Studies
Risk Factors
Young Adult

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