| Diabetes mellitus, periapical inflammation and endodontic treatment outcome. | |
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MedLine Citation:
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PMID: 22143698 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The possible connection between chronic oral inflammatory processes, such as apical periodontitis and periodontal disease (PD), and systemic health is one of the most interesting aspects faced by the medical and dental scientific community. Chronic apical periodontitis shares important characteristics with PD: 1) both are chronic infections of the oral cavity, 2) the Gram-negative anaerobic microbiota found in both diseases is comparable, and 3) in both infectious processes increased local levels of inflammatory mediators may have an impact on systemic levels. One of the systemic disorders linked to PD is diabetes mellitus (DM); is therefore plausible to assume that chronic apical periodontitis and endodontic treatment are also associated with DM. The status of knowledge regarding the relationship between DM and endodontics is reviewed. Upon review, we conclude that there are data in the literature that associate DM with a higher prevalence of periapical lesions, greater size of the osteolityc lesions, greater likelihood of asymptomatic infections and worse prognosis for root filled teeth. The results of some studies suggest that periapical disease may contribute to diabetic metabolic dyscontrol. |
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Authors:
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J-J Segura-Egea; L Castellanos-Cosano; G Machuca; J López-López; J Martín-González; E Velasco-Ortega; B Sánchez-Domínguez; F-J López-Frías |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-6 |
Journal Detail:
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Title: Medicina oral, patologia oral y cirugia bucal Volume: - ISSN: 1698-6946 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231694 Medline TA: Med Oral Patol Oral Cir Bucal Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Dpto. Estomatología, Universidad de Sevilla, C/ Avicena s/n, 41009 Sevilla (SPAIN), segurajj@us.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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