Document Detail


Diabetes mellitus in nonhuman primates: recent research advances and current husbandry practices.
MedLine Citation:
PMID:  2254913     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primates can be utilized for a variety of studies to give insight into the mechanisms of the onset and progression of diabetes mellitus and obesity, and into the development of secondary manifestations. Results can be used to understand the etiologies and effects of diabetes in human beings. Investigators and animal care personnel should be continually aware of the potential for development of diabetes among primates and should seek to identify the earlier stages before the appearance of overt diabetes. In addition to updating recent research in which nonhuman primates have been used in studies on the different forms of diabetes, this review also furnishes some information about therapeutic management and husbandry of monkeys with predispositions toward diabetes or with overt diabetes.
Authors:
C F Howard; M Yasuda
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Journal of medical primatology     Volume:  19     ISSN:  0047-2565     ISO Abbreviation:  J. Med. Primatol.     Publication Date:  1990  
Date Detail:
Created Date:  1991-01-23     Completed Date:  1991-01-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0320626     Medline TA:  J Med Primatol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  609-25     Citation Subset:  IM    
Affiliation:
Division of Primate Medicine, Oregon Regional Primate Research Center, Beaverton.
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MeSH Terms
Descriptor/Qualifier:
Amyloidosis / veterinary*
Animals
Diabetes Mellitus, Type 1 / diagnosis,  drug therapy,  veterinary*
Diabetes Mellitus, Type 2 / diagnosis,  drug therapy,  veterinary*
Disease Models, Animal*
Glucose Tolerance Test / veterinary
Insulin / therapeutic use
Primates*
Grant Support
ID/Acronym/Agency:
DK-21982/DK/NIDDK NIH HHS; RR-00163/RR/NCRR NIH HHS; RR-05694/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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