| Diabetes mellitus in genetically isolated populations in Jordan: prevalence, awareness, glycemic control, and associated factors. | |
| | |
MedLine Citation:
|
PMID: 22502937 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVES: Diabetes mellitus is one of the most common non-communicable diseases globally. This study seeks to estimate the prevalence of impaired fasting glycemia and type 2 diabetes mellitus in genetically isolated populations in Jordan: the Circassians and Chechans. RESEARCH DESIGN AND METHODS: Data were analyzed from a cross-sectional study that included a random sample of adult Circassians and Chechans. A subject was defined as affected by diabetes mellitus if diagnosis was known to patient or, according to the American Diabetes Association definition. Impaired fasting glucose was defined as a fasting serum glucose level of ≥6.1 mmol/L (100 mg/dl) but <7 mmol/L. HbA(1c) >7% was defined as 'unsatisfactory' metabolic control. RESULTS: The prevalence of impaired fasting glycemia was 18.5% for Circassians and 14.6% for Chechans. Prevalence of diabetes was 9.6% for Circassians and 10.1% for Chechans. The prevalence of impaired fasting glycemia and diabetes were significantly higher in men, older age groups, married, subjects of lower educational level, past smokers, and subjects with obesity. Low high-density lipoprotein cholesterol was the most common abnormality in the two populations. CONCLUSIONS: The homogenous, genetically isolated Circassian and Chechan populations sharing the same environmental influences suggest a role for genetic risk factors for diabetes. Thus these two populations are suitable for additional genetics studies that may lead to the identification of novel risk factors for type 2 diabetes. In addition, more than half of patients with diabetes were with unsatisfactory control. Therefore, they are likely to benefit from programs encouraging healthy weight and physical activity. |
| | |
Authors:
|
Rana Dajani; Yousef S Khader; Raja Fatahallah; Mohammad El-Khateeb; Abel Halim Shiyab; Nancy Hakooz |
Related Documents
:
|
22338097 - The risk of a persistent glucose metabolism impairment after gestational diabetes melli... 20110547 - Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in indiv... 22628597 - The outcome of carpal tunnel decompression in patients with diabetes mellitus. 22326357 - A bioactivity guided study on the antidiabetic activity of juniperus oxycedrus subsp. o... 3528667 - Pancreatic insulin secretion in exocrine pancreatic cancer. 12643207 - Treatment of hypertension in diabetic patients with nephropathy. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-4-11 |
Journal Detail:
|
Title: Journal of diabetes and its complications Volume: - ISSN: 1873-460X ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
|
Created Date: 2012-4-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9204583 Medline TA: J Diabetes Complications Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Biology and Biotechnology, Hashemite University, Zarqa, Jordan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Public procurement of health technologies in Greece in an era of economic crisis.
Next Document: Time-course changes in nerve conduction velocity (NCV) in type 2 diabetes.