| Diabetes mellitus adversely affects the outcomes of thrombolytic therapy in patients with acute myocardial infarction. | |
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MedLine Citation:
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PMID: 12934765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study was performed to evaluate whether coexistent diabetes mellitus has any adverse effect on the outcomes of thrombolytic therapy in patients with acute myocardial infarction. Although the early reperfusion rates were similar between the two groups of patients who had acute myocardial infarction with and without diabetes mellitus (42% vs 45.4%, p > 0.05), the results of late angiographic examination showed a significantly lower rate of patency in infarct-related coronary artery (defined as TIMI 3 flow) in diabetics compared to nondiabetics (28.9% vs 41.3%, p < 0.001). The global left ventricular function was also poorer in diabetics (left ventricular wall motion score was 18.6 +/- 7.3 in diabetics and 14.1 +/- 4.6 in nondiabetics, p < 0.01). |
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Authors:
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Hakan Tikiz; Ugur Tezcan; Mehmet Ileri; Yücel Balbay; Ramazan Atak; Emine Kütük |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Angiology Volume: 54 ISSN: 0003-3197 ISO Abbreviation: Angiology Publication Date: 2003 Jul-Aug |
Date Detail:
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Created Date: 2003-08-25 Completed Date: 2003-09-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0203706 Medline TA: Angiology Country: United States |
Other Details:
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Languages: eng Pagination: 449-56 Citation Subset: IM |
Affiliation:
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University of Celal Bayar, Department of Cardiology, Manisa, Turkey. hakancant@superonline.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiomyopathies
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complications*,
drug therapy*,
physiopathology Collateral Circulation / physiology Coronary Angiography Coronary Disease / radiography Diabetes Complications* Diabetes Mellitus / physiopathology Electrocardiography Female Fibrinolytic Agents / therapeutic use* Humans Male Middle Aged Streptokinase / therapeutic use* Thrombolytic Therapy* Tissue Plasminogen Activator / therapeutic use* Ventricular Function, Left / physiology |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; EC 3.4.-/Streptokinase; EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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