| Diabetes insipidus, Sheehan's syndrome and pregnancy. | |
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MedLine Citation:
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PMID: 9578279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To study the role of vasopressin in osmoregulation in two successive pregnancies in a woman with Sheehan's syndrome. STUDY DESIGN: Diabetes insipidus (DI) became manifest during two pregnancies in a woman with postpartum hypopituitarism. RESULTS: Water deprivation-vasopressin administration tests demonstrated partial central DI, corrected with vasopressin in week 12, but only with desmopressin in the third trimester, when placental cystylamino peptidase (vasopressinase) contributes to the severity of the DI. CONCLUSION: If DI occurs during pregnancy it may be the first manifestation of a latent central DI, which is often idiopathic, but rarely the first symptom of a pituitary or hypothalamic abnormality. It may also be part of Sheehan's syndrome. |
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Authors:
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J W Briet |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 77 ISSN: 0301-2115 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-06-11 Completed Date: 1998-06-11 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 201-3 Citation Subset: IM |
Affiliation:
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Department of obstetrics and gynaecology, Geertruiden Hospital, Deventer, Netherlands. gyndev@knmg.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cystinyl Aminopeptidase / metabolism Deamino Arginine Vasopressin / administration & dosage, therapeutic use Diabetes Insipidus / complications, diagnosis*, drug therapy Female Gestational Age Humans Hypopituitarism / complications, diagnosis* Osmolar Concentration Ovulation Induction Placenta / enzymology Pregnancy Pregnancy Complications* Urine Vasopressins / diagnostic use Water Deprivation |
| Chemical | |
Reg. No./Substance:
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11000-17-2/Vasopressins; 16679-58-6/Deamino Arginine Vasopressin; EC 3.4.11.3/Cystinyl Aminopeptidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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