| [Diabetes and heart failure: a practically oriented critical appraisal]. | |
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MedLine Citation:
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PMID: 22354800 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Patients with type 2 diabetes have an increased risk for developing symptoms of heart failure. These can be accompanied by a reduction of left ventricular ejection fraction (HFREF, systolic heart failure) or by a preserved function (HFPEF, diastolic heart failure). The pathophysiology of both entities is distinct and involves impairment of myocardial metabolism and coronary circulation alike. Although diabetes and heart failure often coincide, the management of these patients particularly with respect to the specific benefits or possible hazards of antidiabetic treatment is vague. Therefore, from a pathophysiological as well as clinical viewpoint, 1) diabetic patients with symptoms of heart failure have to be differentiated regarding systolic as well as diastolic left ventricular function by echocardiography and tissue doppler imaging. 2) Heart failure in diabetic patients needs similar attention due to a prognosis and interactions. 3) Optimized blood glucose lowering in combination with improvement of other cardiovascular risk factors is evident for HFREF and is assumed to be beneficial for HFPEF. 4) Antidiabetic medication has to be specifically adapted for both entities. As prospective, controlled studies are scarce, future interventional studies should specifically focus on clinical outcome in diabetic patients with different entities of heart failure. |
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Authors:
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M Halle; A K Gitt; M Hanefeld; M Kellerer; N Marx; J J Meier; P-M Schumm-Draeger; P Bramlage; D Tschoepe |
Publication Detail:
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Type: English Abstract; Journal Article Date: 2012-02-21 |
Journal Detail:
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Title: Deutsche medizinische Wochenschrift (1946) Volume: 137 ISSN: 1439-4413 ISO Abbreviation: Dtsch. Med. Wochenschr. Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-02-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0006723 Medline TA: Dtsch Med Wochenschr Country: Germany |
Other Details:
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Languages: ger Pagination: 437-41 Citation Subset: IM |
Copyright Information:
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© Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
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Zentrum für Prävention und Sportmedizin an der TU München. |
Vernacular Title:
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Diabetes und Herzinsuffizienz: eine praxisorientierte, kritische Bestandsaufnahme. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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