| Diabetes and fracture healing: the skeletal effects of diabetic drugs. | |
| | |
MedLine Citation:
|
PMID: 22145960 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Introduction: Over 39,000 diabetic patients are surgically treated for trauma and orthopaedic injuries annually in the UK, yet the effects of diabetic medications on the skeletal system is an under researched and under acknowledged field. Areas covered: This review covers all English language novel experimental data reports investigating the effects of the main classes of diabetic drugs on the skeletal system, specifically their effects on fracture healing, located through the literature search engines Medline and Web of Science. Expert opinion: Post-surgical gylcaemic control is paramount in insulin-controlled type 1 diabetic patients. Data on pharmacological control compounds used in type 2 diabetes are limited. Reports to date indicate thiazolidinediones to exert anti-osteogenic effects, in contrast to the observed osteogenic effects of biguanides. Ongoing research is desirable to guide future clinical recommendations. |
| | |
Authors:
|
Christopher M Simpson; Giorgio M Calori; Peter V Giannoudis |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-6 |
Journal Detail:
|
Title: Expert opinion on drug safety Volume: - ISSN: 1744-764X ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-12-7 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101163027 Medline TA: Expert Opin Drug Saf Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
University of Leeds, Leeds Teaching Hospitals NHS Trust, School of Medicine , Academic Dept. of Trauma and Orthopaedics , Leeds , UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Infectious complications in adult acute myeloid leukemia: Analysis of the prospective multicenter cl...
Next Document: The Temperature Dependence of Ion Transport in Dilute Tetrabutylammonium Triflate-Acetate Solutions ...