Document Detail

Diabetes does not affect long-term results after total arterial off-pump coronary revascularization.
MedLine Citation:
PMID:  20868811     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We evaluated the influence of diabetes mellitus (DM) on 5-year angiographic results and long-term clinical outcomes in patients who underwent total arterial off-pump coronary revascularization for multivessel coronary disease. METHODS: Between January 1998 and July 2004, total arterial revascularization for multivessel coronary disease was performed in 558 patients; 247 patients were diabetic (DM group) and 311 were nondiabetic (NDM group). Follow-up duration was 81 ± 26 months. Long-term survival, cardiac deaths, and major advanced cardiovascular or cerebral events were studied. Effects of DM on early, 1-year, and 5-year graft patency rates were compared using the generalized linear mixed model. RESULTS: No differences in operative mortality and morbidity were observed. Overall survival in the DM group was significantly lower (p = 0.004), with 10-year survival rates of 78.5% (vs 88.1% in the NDM group). Independent risk factors for long-term survival included smoking, chronic renal failure, and preoperative left ventricular dysfunction, but not DM itself. No differences in freedom from cardiac death were found between the 2 groups (p = 0.171). Freedom from reintervention and major adverse cardiovascular and cerebral events were also similar between the groups. Early, 1-year, and 5-year postoperative angiographic patency rates in the DM group were 98.2%, 95.3%, and 94.6%, respectively. Those of the NDM group were 98.6%, 94.7%, and 90.5%. Diabetes mellitus did not affect graft patency rates. CONCLUSIONS: Diabetes mellitus did not affect 5-year angiographic results, long-term survival, and clinical events in patients with multivessel coronary disease who underwent total arterial off-pump revascularization.
Ho Young Hwang; Jae-Sung Choi; Ki-Bong Kim
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  90     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2010-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1180-6     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Korea.
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MeSH Terms
Coronary Angiography
Coronary Artery Bypass, Off-Pump*
Coronary Disease / complications,  radiography,  surgery*
Diabetes Complications*
Middle Aged
Retrospective Studies
Treatment Outcome
Vascular Patency

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