Document Detail

Diabetes as a risk factor for myocardial infarction: population and gender perspectives.
MedLine Citation:
PMID:  10497624     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To investigate diabetes as a risk factor for acute myocardial infarction (AMI) from a population perspective in a region with high cardiovascular disease (CVD) risk. DESIGN: Population screenings for diabetes and a population-based AMI register. SETTING: Northern Sweden MONICA area. SUBJECTS: Representative sample (Norrbotten and Västerbotten counties) of 2432 men and women 35-64 years was investigated 1990 and 1994. All patients with AMI aged 35-64 years were included, in total 3031 between 1989 and 1993. RESULTS: The prevalence of diabetes was 5% in men and 4.4% in women. The relative risk (RR) in diabetic men was 2.9; 95% confidence interval (CI) 2.6-3.4, and in diabetic women, RR 5.0; CI 3.9-6.3. The risk for re-infarction was about twice as large in patients with diabetes as in patients without diabetes. In both sexes the overall 28 day case fatality (CF) was significantly higher in diabetic compared to non-diabetic subjects. When compared to the non-diabetic population, the overall mortality from AMI in the diabetic population was 4 times higher among men and 7 times higher among women. The population attributable risk (PAR), a crude estimate of all AMIs ascribed to diabetes, was 11% in men and 17% in women. CONCLUSIONS: Diabetes increases the risk for AMI attack rate, incidence, case-fatality, recurrence and mortality and is an important contributor to all AMIs in middle-aged people.
V Lundberg; B Stegmayr; K Asplund; M Eliasson; F Huhtasaari
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of internal medicine     Volume:  241     ISSN:  0954-6820     ISO Abbreviation:  J. Intern. Med.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1999-10-13     Completed Date:  1999-10-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8904841     Medline TA:  J Intern Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  485-92     Citation Subset:  IM    
Department of Medicine, Kalix Hospital, Sweden.
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MeSH Terms
Diabetes Complications*
Diabetes Mellitus / epidemiology
Middle Aged
Myocardial Infarction / epidemiology*,  etiology*,  mortality
Risk Factors
Sweden / epidemiology

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