Document Detail


Diabetes as a risk factor for cardiac conduction defects: a review.
MedLine Citation:
PMID:  17391152     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Diabetes mellitus (DM) is a major risk factor for cardiovascular disease and mortality with increasing prevalence in the ageing population. Coronary artery disease is the major cardiovascular abnormality in DM patients. Cardiomyopathy and left ventricular hypertrophy are two other known associated cardiovascular abnormalities. There are a few non-randomized studies reporting increased prevalence of cardiac conduction abnormalities, such as right bundle branch block (RBBB), bifascicular block and high degree atrioventricular (AV)-block but not left bundle branch block (LBBB), in DM patients. Most clinicians are not aware of this association, and it is rarely mentioned in the published reviews about cardiovascular abnormalities in this population. The cause of cardiac conduction abnormalities in DM patients is not known. If autonomic neuropathy or DM-associated cardiovascular disease plays a role, it remains unknown. The goal of this manuscript is to review the current literature about the risk of conduction abnormalities in DM patients. For this study, Medline, Google and published books were searched and reviewed for any references that matched cardiac conduction abnormalities, AV-block, BBB for bundle branch block, LBBB, RBBB, bifascicular block, autonomic neuropathy and DM.
Authors:
Mohammad-Reza Movahed
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Diabetes, obesity & metabolism     Volume:  9     ISSN:  1462-8902     ISO Abbreviation:  Diabetes Obes Metab     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-03-29     Completed Date:  2007-06-22     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  100883645     Medline TA:  Diabetes Obes Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  276-81     Citation Subset:  IM    
Affiliation:
Department of Medicine, Division of Cardiology, University of California, Irvine Medical Center, Orange, CA 92868-4080, USA. rmovd@aol.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / complications,  physiopathology*,  prevention & control
Autonomic Nervous System Diseases / complications,  physiopathology*
Bundle-Branch Block / complications,  physiopathology,  prevention & control
Diabetes Complications / physiopathology*
Heart Block / complications,  physiopathology,  prevention & control
Heart Conduction System / physiopathology*
Humans
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Thermogenic and metabolic antiobesity drugs: rationale and opportunities.
Next Document:  Adiponectin in health and disease.