Document Detail


DiGeorge syndrome/velocardiofacial syndrome: the chromosome 22q11.2 deletion syndrome.
MedLine Citation:
PMID:  17712990     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chromosome 22q11.2 deletion (CH22qD) syndrome is also known as DiGeorge syndrome or velocardiofacial syndrome. This deletion syndrome is extremely common with nearly one in 4000 children being affected. Recent advances and a holistic approach to patients have improved the care and well-being of these patients. This review will summarize advances in understanding the health needs and immune system of patients with CH22qD syndrome. Patients will most often need interventions directed at maximizing function for many organ systems but can ultimately have a high level of functioning.
Authors:
Kathleen E Sullivan
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  601     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  2007  
Date Detail:
Created Date:  2007-08-23     Completed Date:  2007-10-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  37-49     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Division of Allergy & Immunology, Children's Hospital of Philadelphia, Philadelphia, PA, USA. sullivak@mail.med.upenn.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Allergy and Immunology
Child
Child, Preschool
Chromosome Deletion
Chromosomes, Human, Pair 22*
DiGeorge Syndrome / diagnosis*,  genetics*,  immunology
Gene Deletion*
Humans
Infant
Infant, Newborn
Models, Genetic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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