Document Detail


Dextran stabilized iron oxide nanoparticles: Synthesis, characterization and in vitro studies.
MedLine Citation:
PMID:  23218360     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Iron oxide nanoparticles are one of the most important genres of nanoparticles with promise. Dextran, a stable biocompatible coating agent was employed in the synthesis of iron oxide nanoparticles in the presence of urea. The morphology of nanoparticles was confirmed by dynamic light scattering and transmission electron microscopy. These particles were also assessed for cytotoxicity, cellular uptake and cell adhesion in vitro using murine fibroblast cell line. The synthesized nanoparticles were superparamagnetic, possessed spherical shape with narrow size distribution and were found to be biocompatible and non-toxic. This study serves as a background for using DIONPs in further in vitro and in vivo studies with a long term goal of using it in biological applications.
Authors:
Sheeja Liza Easo; P V Mohanan
Publication Detail:
Type:  Journal Article     Date:  2012-10-08
Journal Detail:
Title:  Carbohydrate polymers     Volume:  92     ISSN:  1879-1344     ISO Abbreviation:  Carbohydr Polym     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8307156     Medline TA:  Carbohydr Polym     Country:  England    
Other Details:
Languages:  eng     Pagination:  726-32     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Division of Toxicology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojapura, Thiruvananthapuram 695012, Kerala, India.
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