Document Detail


Dextran microsphere embolization: experimental and clinical experience with radiologic-pathologic correlation. Work in progress.
MedLine Citation:
PMID:  2426727     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The radiologic and pathologic effects of canine renal embolization with dextran microspheres of two size ranges (40-150 micron and 100-300 micron) were studied 30 minutes and 1, 2, 4, and 6 weeks after embolization. Dramatic occlusions occurred with very small quantities of these particles, which reached more distally and were suspended and embolized more easily than other solid embolic agents. Because of these qualities, however, they should be used with more caution. They can be injected through 2-F catheters, calibrated-leak balloons, and open-ended guide wires. Embolization with dextran microspheres was also used for epistaxis, meningioma, dural arteriovenous malformation, renal tumors, bone metastasis, multiple myeloma, or peripheral angioma in ten patients. The technique was safe and effective, but special attention should be directed to proper dilution and gentle embolization with careful monitoring to avoid excessive embolization or reflux.
Authors:
J E Dion; R N Rankin; F Viñuela; A J Fox; A C Wallace; M Mervart
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Radiology     Volume:  160     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-09-18     Completed Date:  1986-09-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  717-21     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Catheterization / methods
Dextrans / administration & dosage*,  therapeutic use
Dogs
Embolization, Therapeutic / methods*
Fluoroscopy
Follow-Up Studies
Humans
Kidney / blood supply*,  pathology
Meninges / blood supply
Microspheres
Renal Artery / pathology,  radiography*
Chemical
Reg. No./Substance:
9004-54-0/Dextrans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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