Document Detail


Dexmedetomidine sedation in a pediatric cardiac patient scheduled for MRI.
MedLine Citation:
PMID:  16103387     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe the use of dexmedetomidine for sedation in a critically ill infant undergoing magnetic resonance imaging (MRI). CLINICAL FEATURES: A nine-month-old 5.1 kg infant was to have an MRI study of the thorax. The infant had multiple congenital cardiac anomalies which had been partially corrected surgically. After administration of atropine, 0.1 mg iv, a loading dose of dexmedetomidine (1 microg.kg(-1) iv) was administered over ten minutes followed by a continuous infusion of 0.5 microg.kg(-1).hr(-1) for maintenance. Propofol 5 mg iv were administered after the loading dose of dexemedetomidine to produce somnolence. Anesthetic conditions for performing the MRI were excellent. The infant remained motionless, breathing spontaneously. Hemodynamics remained stable throughout the procedure. Recovery was rapid and uneventful. CONCLUSION: Dexmedetomidine and a small dose of propofol were used successfully to sedate a critically ill infant for MRI. More studies are required to determine the role of this unique drug in the pediatric population.
Authors:
Elizabeth T Young
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian journal of anaesthesia = Journal canadien d'anesthésie     Volume:  52     ISSN:  0832-610X     ISO Abbreviation:  Can J Anaesth     Publication Date:    2005 Aug-Sep
Date Detail:
Created Date:  2005-08-16     Completed Date:  2006-02-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701709     Medline TA:  Can J Anaesth     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  730-2     Citation Subset:  IM    
Affiliation:
Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA. Eyoung@ochsner.org
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MeSH Terms
Descriptor/Qualifier:
Anesthesia Recovery Period
Anesthetics, Intravenous / administration & dosage
Blood Pressure / physiology
Critical Illness
Dexmedetomidine / administration & dosage*
Heart Defects, Congenital / diagnosis*
Heart Rate / physiology
Humans
Hypnotics and Sedatives / administration & dosage*
Infant
Infusions, Intravenous
Magnetic Resonance Imaging*
Propofol / administration & dosage
Respiration
Sleep Stages / drug effects
Chemical
Reg. No./Substance:
0/Anesthetics, Intravenous; 0/Hypnotics and Sedatives; 113775-47-6/Dexmedetomidine; 2078-54-8/Propofol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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