Document Detail

Dexmedetomidine and proprofol in complex microlaryngeal surgery in infants.
MedLine Citation:
PMID:  19556016     Owner:  NLM     Status:  MEDLINE    
We describe the case of an infant undergoing endoscopic repair of a laryngeal cleft where the combination of dexmedetomidine and propofol infusions was used as the anesthetic technique. With this regimen, endotracheal intubation was unnecessary during the perioperative period, the procedure lasted approximately 3h, and the child recovered uneventfully. Historically, the techniques used for microlaryngeal surgery involve the use of intermittent endotracheal intubation and insufflation of halogenated anesthetics to the oropharynx. Given the potential benefits of a technique that obviates the need for endotracheal intubation during microlaryngeal surgery and prevents insufflation of halogenated anesthetics in an open environment, the combination of propofol and dexmedetomidine should be considered as a viable and desirable anesthetic option for infants undergoing complex microlaryngeal surgery.
Zenaide M N Quezado; Jan C Groblewski; Harold J Gelfand; Rahul K Shah
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Intramural     Date:  2009-06-24
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  73     ISSN:  1872-8464     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-03     Completed Date:  2009-10-20     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  1311-2     Citation Subset:  IM    
Department of Anesthesia and Surgical Services, NIH Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.
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MeSH Terms
Anesthesia / methods*
Dexmedetomidine / therapeutic use*
Hypnotics and Sedatives / therapeutic use*
Infant, Newborn
Laryngoscopy / methods
Larynx / abnormalities*,  surgery*
Laser Therapy / methods
Microsurgery / methods*
Propofol / therapeutic use*
Reconstructive Surgical Procedures / methods
Grant Support
Reg. No./Substance:
0/Hypnotics and Sedatives; 113775-47-6/Dexmedetomidine; 2078-54-8/Propofol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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