| Dexmedetomidine and proprofol in complex microlaryngeal surgery in infants. | |
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MedLine Citation:
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PMID: 19556016 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe the case of an infant undergoing endoscopic repair of a laryngeal cleft where the combination of dexmedetomidine and propofol infusions was used as the anesthetic technique. With this regimen, endotracheal intubation was unnecessary during the perioperative period, the procedure lasted approximately 3h, and the child recovered uneventfully. Historically, the techniques used for microlaryngeal surgery involve the use of intermittent endotracheal intubation and insufflation of halogenated anesthetics to the oropharynx. Given the potential benefits of a technique that obviates the need for endotracheal intubation during microlaryngeal surgery and prevents insufflation of halogenated anesthetics in an open environment, the combination of propofol and dexmedetomidine should be considered as a viable and desirable anesthetic option for infants undergoing complex microlaryngeal surgery. |
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Authors:
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Zenaide M N Quezado; Jan C Groblewski; Harold J Gelfand; Rahul K Shah |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Intramural Date: 2009-06-24 |
Journal Detail:
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Title: International journal of pediatric otorhinolaryngology Volume: 73 ISSN: 1872-8464 ISO Abbreviation: Int. J. Pediatr. Otorhinolaryngol. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-03 Completed Date: 2009-10-20 Revised Date: 2012-03-08 |
Medline Journal Info:
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Nlm Unique ID: 8003603 Medline TA: Int J Pediatr Otorhinolaryngol Country: Ireland |
Other Details:
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Languages: eng Pagination: 1311-2 Citation Subset: IM |
Affiliation:
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Department of Anesthesia and Surgical Services, NIH Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. zquezado@nih.gov |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia
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methods* Dexmedetomidine / therapeutic use* Humans Hypnotics and Sedatives / therapeutic use* Infant, Newborn Laryngoscopy / methods Larynx / abnormalities*, surgery* Laser Therapy / methods Microsurgery / methods* Propofol / therapeutic use* Reconstructive Surgical Procedures / methods |
| Grant Support | |
ID/Acronym/Agency:
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Z99 CL999999/CL/CLC NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Hypnotics and Sedatives; 113775-47-6/Dexmedetomidine; 2078-54-8/Propofol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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