| Dexmedetomidine modulates cardiovascular responses to stimulation of central nervous system pressor sites. | |
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MedLine Citation:
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PMID: 10072017 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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IMPLICATIONS: A new potential anesthetic adjunct, dexmedetomidine, does not attenuate brain-mediated increases in blood pressure, but the combination of dexmedetomidine and the anesthetic halothane acts to modulate central cardiovascular responses. |
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Authors:
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N E Farber; E Samso; M Staunton; D Schwabe; W T Schmeling |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 88 ISSN: 0003-2999 ISO Abbreviation: Anesth. Analg. Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-03-25 Completed Date: 1999-03-25 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 617-24 Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology, The Medical College of Wisconsin, Milwaukee 53226, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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pharmacology* Anesthetics, Inhalation / pharmacology Animals Blood Pressure / drug effects, physiology Cardiovascular System / innervation* Cats Central Nervous System / drug effects*, physiology Drug Interactions Electric Stimulation Halothane / pharmacology Heart Rate / drug effects, physiology Imidazoles / pharmacology* Medetomidine Pressoreceptors / drug effects*, physiology Receptors, Adrenergic, alpha-2 / physiology |
| Grant Support | |
ID/Acronym/Agency:
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R01 GM 56398-01/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 0/Anesthetics, Inhalation; 0/Imidazoles; 0/Receptors, Adrenergic, alpha-2; 151-67-7/Halothane; 86347-14-0/Medetomidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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