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Dexmedetomidine as the primary anesthetic agent during cardiac surgery in an infant with a family history of malignant hyperthermia.
MedLine Citation:
PMID:  22144934     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Malignant hyperthermia (MH) is an acute hypermetabolic crisis triggered in susceptible patients by the administration of succinylcholine or a volatile anesthetic agent. When providing anesthetic care for MH-susceptible agents, a total intravenous anesthetic (TIVA) technique is frequently chosen. When choosing the components for TIVA, several options exist including the combination of propofol or dexmedetomidine with an opioid. We present our experience with the use of dexmedetomidine as a key component of the anesthetic regimen in a 5-month-old infant with a family history of MH. Previous reports of the use of dexmedetomidine in MH-susceptible patients are reviewed and its benefits in such patients discussed.
Authors:
Aymen Naguib; Chris McKee; Alistair Phillips; Joseph D Tobias
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi journal of anaesthesia     Volume:  5     ISSN:  0975-3125     ISO Abbreviation:  Saudi J Anaesth     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-12-06     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101500601     Medline TA:  Saudi J Anaesth     Country:  India    
Other Details:
Languages:  eng     Pagination:  426-9     Citation Subset:  -    
Affiliation:
Department of Anesthesiology and Pediatrics, Nationwide Children's Hospital and the Ohio State University, Columbus, Ohio, USA.
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