Document Detail

Device therapies: new indications and future directions.
MedLine Citation:
PMID:  25391852     Owner:  NLM     Status:  In-Data-Review    
Implantable cardioverter-defibrillator (ICDs), cardiac resynchronization (CRT) and combination (CRT-D) therapy have become an integral part of the management of patients with heart failure with reduced ejection fraction (HFrEF). ICDs treat ventricular arrhythmia and CRTs improve left ventricular systolic function by resynchronizing ventricular contraction. Device therapies (ICD, CRT-D), have been shown to reduce all-cause mortality, including sudden cardiac death. Hospitalizations are reduced with CRT and CRT-D therapy. Major device related complications include device infection, inappropriate shocks, lead malfunction and complications related to extraction of devices. Improvements in device design and implantation have included progressive miniaturization and increasing battery life of the device, optimization of response to CRT, and minimizing inappropriate device therapy. Additionally, better definition of the population with the greatest benefit is an area of active research.
Prabhat Kumar; Jennifer D Schwartz
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current cardiology reviews     Volume:  11     ISSN:  1875-6557     ISO Abbreviation:  Curr Cardiol Rev     Publication Date:  2015  
Date Detail:
Created Date:  2014-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101261935     Medline TA:  Curr Cardiol Rev     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  33-41     Citation Subset:  IM    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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