| Devic-like syndrome in the course of pulmonary tuberculosis. | |
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MedLine Citation:
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PMID: 20873452 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Optic neuromyelitis or Devic's syndrome is a very rare disease affecting the optic tracts and the spinal cord. Its association with evolving pulmonary tuberculosis has been reported in a handful of case reports. CASE REPORT: The authors report two cases of Devic's syndrome associated pulmonary tuberculosis (48 and 43 years old men). The First patient was experiencing evolving pulmonary tuberculosis. The two patients were admitted for bilateral blindness followed by paraplegia and sphincter disturbance. Clinical examination and investigations excluded direct tuberculous involvement of the nervous system or a reaction to antituberculous therapy and Devic's syndrome was diagnosed, based on Wingerchurk's criteria. Following treatment with corticosteroids and antituberculous chemotherapy, we noted partial recovery of motor symptoms and sphincter control but the patients remained completely blind. CONCLUSIONS: Throughout this case report, the authors emphasize the rarity of this association and discuss the pathophysiological mechanism, which appears to be an immune dysfunction triggered by mycobacterium infection. |
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Authors:
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M A Rafai; F Z Boulaajaj; M Gynerane; B El Moutawakkil; I Slassi |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta neurologica Belgica Volume: 110 ISSN: 0300-9009 ISO Abbreviation: Acta Neurol Belg Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-09-29 Completed Date: 2010-10-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0247035 Medline TA: Acta Neurol Belg Country: Belgium |
Other Details:
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Languages: eng Pagination: 196-200 Citation Subset: IM |
Affiliation:
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Service de Neurologie - Explorations Fonctionnelles, CHU Ibn Rochd, Quartier des Hôpitaux, Casablanca, Maroc. neuroblanca@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use Adult Antitubercular Agents / therapeutic use Humans Magnetic Resonance Imaging Male Middle Aged Neuromyelitis Optica / complications*, diagnosis Radiography / methods Radiography, Thoracic Spinal Cord / pathology Tuberculosis, Pulmonary / complications*, diagnosis, drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Antitubercular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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