Document Detail


Developmental testing of the Advanced Animal Habitat to determine compatibility with rats and mice.
MedLine Citation:
PMID:  11538901     Owner:  NASA     Status:  MEDLINE    
Abstract/OtherAbstract:
The Research Animal Holding Facility (RAHF) and the Animal Enclosure Module (AEM) have housed rats during Space Shuttle flights since the 1980s, but the operational constraints of the hardware have limited the scientific return from these Shuttle flights. The RAHF provides environmental control and monitoring for 24 rats with in-flight animal access, but it must be flown in the Spacelab. Due to the infrequent availability of Spacelab flights, rodent experiments rely heavily on the AEM. Unfortunately, the AEM supports only six rats, has no environmental control and provides no animal access in flight. The Advanced Animal Habitat (AAH) is being developed to support up to 12 adult rats or 30 adult mice for up to 30 days, provide active temperature control, animal telemetry and on-orbit video, record environmental parameters in the animal cage, and provide in-flight animal access in the Middeck, the Spacelab or the Space Station. To ensure the AAH can meet these requirements, animal testing is being conducted with rats and mice in every step of development. Testing began with the cage configuration.
Authors:
B J Corbin; L A Baer; R E Grindeland; M Vasques
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology     Volume:  2     ISSN:  1077-9248     ISO Abbreviation:  J Gravit Physiol     Publication Date:  1995  
Date Detail:
Created Date:  1996-10-17     Completed Date:  1996-10-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9437868     Medline TA:  J Gravit Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  P141-2     Citation Subset:  S    
Affiliation:
NASA Ames Research Center, Moffett Field, CA 94035, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Behavior, Animal*
Body Weight
Drinking
Eating
Equipment Design
Evaluation Studies as Topic
Female
Housing, Animal / standards*
Liver / anatomy & histology
Male
Mice
Organ Size*
Population Density
Rats
Rats, Sprague-Dawley
Spacecraft / instrumentation
Thymus Gland / anatomy & histology
Investigator
Investigator/Affiliation:
R E Grindeland / ARC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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