| Developmental regulation of cytokeratins in cells of the rat mammary gland studied with monoclonal antibodies. | |
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MedLine Citation:
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PMID: 6199793 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have isolated two monoclonal antibodies to cytokeratins and determined their cell specificities. They display interesting localization within the rat mammary gland. One (1A10) shows specificity for myoepithelial cells; the other (24B42) is specific for lumenal cells at various stages of development. These two monoclonal antibodies and three others to cytokeratin previously isolated were used in conjunction with antibodies to myosin and collagen IV to confirm and extend our previous findings on epithelial cell types and development within the mammary gland. |
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Authors:
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R Allen; R Dulbecco; P Syka; M Bowman; B Armstrong |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 81 ISSN: 0027-8424 ISO Abbreviation: Proc. Natl. Acad. Sci. U.S.A. Publication Date: 1984 Feb |
Date Detail:
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Created Date: 1984-04-24 Completed Date: 1984-04-24 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 7505876 Medline TA: Proc Natl Acad Sci U S A Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1203-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging Animals Antibodies, Monoclonal Female Fluorescent Antibody Technique Histocytochemistry Immunoenzyme Techniques Keratins / metabolism* Male Mammary Glands, Animal / growth & development* Rats Tissue Distribution |
| Grant Support | |
ID/Acronym/Agency:
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1-R01CA21993/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 68238-35-7/Keratins |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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