Document Detail

Developmental patterns from 1 to 4 years of extremely preterm infants who required home oxygen therapy.
MedLine Citation:
PMID:  16860947     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Bronchopulmonary dysplasia (BPD) remains a common complication of prematurity, with those being discharged on home oxygen at particularly high risk of adverse developmental outcomes. AIMS: To compare the developmental patterns, from 1 to 4 years, of extremely preterm infants with BPD discharged from hospital on home oxygen, extremely preterm infants with BPD discharged breathing room air, and extremely preterm infants without BPD. SUBJECTS: Two hundred and seventy-six infants with a gestational age of <28 weeks or birthweight <1000 g, free from sensory and motor disabilities who were followed up longitudinally to 4 years corrected age. OUTCOME MEASURES: Children were assessed on the Griffiths Mental Development Scales at 1 and 2 years corrected age, and the McCarthy Scales of Children's Abilities at 4 years corrected age. RESULTS: The developmental trajectories of the three groups did not differ significantly, however at 1 year corrected age the non-BPD group had significantly higher developmental scores than both BPD groups. At 2 years corrected age the non-BPD group had significantly higher developmental scores than the BPD-home oxygen group, and at 4 years corrected age no differences between the groups were evident. CONCLUSIONS: Extremely preterm children with BPD exhibited an initial developmental lag compared to preterm peers. Children with BPD discharged breathing room air had developmental scores at 2 years corrected age that were comparable to the non-BPD group, but those discharged on home oxygen still had lower developmental scores. At 4 years, no differences between the groups were evident.
Natasha M Moon; Heather A Mohay; Peter H Gray
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Publication Detail:
Type:  Journal Article     Date:  2006-07-24
Journal Detail:
Title:  Early human development     Volume:  83     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-26     Completed Date:  2007-06-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  209-16     Citation Subset:  IM    
Queensland University of Technology, School of Psychology and Counselling, Beams Road Carseldine, Qld. 4034, Australia.
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MeSH Terms
Bronchopulmonary Dysplasia / complications,  therapy*
Child Development*
Child, Preschool
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / therapy*
Oxygen Inhalation Therapy*

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