Document Detail

Developmental outcomes at the age of two years for very premature babies managed with nasal prong continuous positive airway pressure.
MedLine Citation:
PMID:  17535180     Owner:  NLM     Status:  MEDLINE    
AIMS: To describe the developmental progress of very premature babies at the age of 2 years, who were managed in an era where nasal prong continuous positive airway pressure (CPAP) was the preferred method for the management of initial respiratory disease. METHODS: Two groups of very premature babies of <32 weeks gestation were compared, the first being managed with an intubation and mandatory ventilation approach, and the second being managed with a CPAP approach. The groups are compared with regard to the presence of brain injury, retinopathy and requiring discharge home on oxygen and then at 2 years, for language impairment, non-ambulatory cerebral palsy and significant developmental delay. The study is designed as an audit of data collected prospectively and longitudinally for babies born from 1998 to 2002. RESULTS: A significant number of babies were successfully managed on CPAP in the second era and significantly fewer received post-natal steroids. The number being discharged home on oxygen, brain injury and retinopathy were similar in the two groups. Developmental outcome assessed at 2 years of age was the same in both eras. CONCLUSIONS: A CPAP approach to the management of initial respiratory disease in premature babies of less than 32 weeks gestation at birth is associated with no measurable developmental advantage or disadvantage at 2 years of age.
Jacqueline A Stack; Bin Jalaludin
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  43     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-30     Completed Date:  2008-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  480-5     Citation Subset:  IM    
Department of Newborn Care, Liverpool Hospital, Sydney South West Area Health Service, Liverpool, NSW, Australia.
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MeSH Terms
Cerebral Palsy / physiopathology
Child, Preschool
Continuous Positive Airway Pressure / instrumentation*
Gestational Age
Infant, Newborn
Infant, Premature*
Infant, Very Low Birth Weight*
Language Development Disorders / physiopathology
Longitudinal Studies
Oxygen Inhalation Therapy
Prospective Studies
Respiratory Distress Syndrome, Newborn / therapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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