Document Detail


Developmental delay in congenital myotonic dystrophy after neonatal intensive care.
MedLine Citation:
PMID:  1694755     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Six infants with congenital myotonic dystrophy survived after neonatal intensive care. In later childhood they were assessed by the Griffiths Mental Development Scales: five children were functioning in the mildly handicapped to borderline range of development (DQ 64.0 to 79.0) and the remaining child was severely delayed in development (DQ 33.0). The five children with higher DQ values had a history of ventilatory support of 30 days or less after birth. By contrast, the remaining child with the lowest DQ value had been ventilated for 43 days. This study provides further evidence that prolonged ventilation after birth has prognostic significance in identifying severely affected cases with congenital myotonic dystrophy.
Authors:
A Nicholson; E Rivlin; D G Sims; M L Chiswick; S W D'Souza
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Early human development     Volume:  22     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-08-13     Completed Date:  1990-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  99-103     Citation Subset:  IM    
Affiliation:
Department of Child Health, St. Mary's Hospital, Manchester, U.K.
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Developmental Disabilities / etiology*
Humans
Infant
Myotonic Dystrophy / congenital*
Respiration, Artificial / adverse effects

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