Document Detail

Developmental changes in sleep and their relationships to psychiatric illnesses.
MedLine Citation:
PMID:  24060918     Owner:  NLM     Status:  In-Data-Review    
PURPOSE OF REVIEW: Sleep undergoes major changes during development. Its relationship to the complex process of maturation in health and disease has recently received increased attention. This review aims to highlight the recent literature examining the interplay of altered sleep, brain development and emerging psychiatric illnesses in children and adolescents.
RECENT FINDINGS: In addition to a temporal relationship of sleep disturbances preceding the onset of psychiatric illnesses, a bi-directional interaction of altered sleep and symptom severity has increasingly been shown. Sleep architecture shows drastic age-dependent alterations on a structural level during the first 2 decades of life. However, findings regarding disease-specific patterns have remained inconsistent. On a functional level, recent evidence about sleep electroencephalographic characteristics points to a close relationship between slow waves, reflecting the depth of sleep, and cortical plasticity.
SUMMARY: Sleep provides a rich source of information to gain insight into both the healthy and disturbed processes of brain function and maturation. Emerging data suggest that the investigation of slow wave activity is a novel and promising tool for monitoring both of these processes. It is important to understand when and how deviations from typical developmental sleep alterations occur in order to improve prevention and early treatment of disorders affecting a substantial number of children and adolescents.
Noemi Tesler; Miriam Gerstenberg; Reto Huber
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current opinion in psychiatry     Volume:  26     ISSN:  1473-6578     ISO Abbreviation:  Curr Opin Psychiatry     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-09-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809880     Medline TA:  Curr Opin Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  572-9     Citation Subset:  IM    
aChild Development Center, University Children's Hospital Zurich bDepartment of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland *Shared first authorship.
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