Document Detail

Developmental change in fetal response to repeated low-intensity sound.
MedLine Citation:
PMID:  18171366     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to investigate developmental changes in heart rate response to repeated low-intensity (85 dB) sound stimulation in fetuses between 32 and 37 weeks of gestation. We measured amplitude changes in heart rate as our index of fetal response. At 35 to 37 weeks of gestation, the majority of fetuses showed a deceleratory response at the first trial. Amplitude decreased with further trials using the same stimulus before recovering when exposed to another type of stimulation. In contrast, responses in fetuses at 32 to 34 weeks of gestation were variable across trials and there was no recovery with exposure to another type of stimulation. Our results suggest that fetal habituation of cardiac response changes with developmental age.
Seiichi Morokuma; Valentina Doria; Antonio Ierullo; Naoko Kinukawa; Kotaro Fukushima; Hitoo Nakano; Sabaratnam Arulkumaran; Aris T Papageorghiou
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental science     Volume:  11     ISSN:  1467-7687     ISO Abbreviation:  Dev Sci     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-03     Completed Date:  2008-03-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9814574     Medline TA:  Dev Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  47-52     Citation Subset:  IM    
Fetal Medicine Unit, Department of Obstetrics and Gynaecology, St George's Hospital, London University, UK.
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MeSH Terms
Acoustic Stimulation*
Age Factors
Fetal Development / physiology*
Fetus / physiology*
Gestational Age
Habituation, Psychophysiologic / physiology
Heart Rate, Fetal / physiology*

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