| Development and validation of a magneto-hydrodynamic solver for blood flow analysis. | |
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MedLine Citation:
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PMID: 21081822 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The objective of this study was to develop a numerical solver to calculate the magneto-hydrodynamic (MHD) signal produced by a moving conductive liquid, i.e. blood flow in the great vessels of the heart, in a static magnetic field. We believe that this MHD signal is able to non-invasively characterize cardiac blood flow in order to supplement the present non-invasive techniques for the assessment of heart failure conditions. The MHD signal can be recorded on the electrocardiogram (ECG) while the subject is exposed to a strong static magnetic field. The MHD signal can only be measured indirectly as a combination of the heart's electrical signal and the MHD signal. The MHD signal itself is caused by induced electrical currents in the blood due to the moving of the blood in the magnetic field. To characterize and eventually optimize MHD measurements, we developed a MHD solver based on a finite element code. This code was validated against literature, experimental and analytical data. The validation of the MHD solver shows good agreement with all three reference values. Future studies will include the calculation of the MHD signals for anatomical models. We will vary the orientation of the static magnetic field to determine an optimized location for the measurement of the MHD blood flow signal. |
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Authors:
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W Kainz; J Guag; S Benkler; D Szczerba; E Neufeld; V Krauthamer; J Myklebust; H Bassen; I Chang; N Chavannes; J H Kim; M Sarntinoranont; N Kuster |
Publication Detail:
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Type: Journal Article Date: 2010-11-16 |
Journal Detail:
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Title: Physics in medicine and biology Volume: 55 ISSN: 1361-6560 ISO Abbreviation: Phys Med Biol Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 7253-61 Citation Subset: IM |
Affiliation:
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Center for Devices and Radiological Health, FDA, Silver Spring, MD, USA. wolfgang.kainz@fda.hhs.gov |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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