Document Detail


Development and validation of a food frequency questionnaire for the assessment of dietary total antioxidant capacity.
MedLine Citation:
PMID:  17182807     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The total antioxidant capacity (TAC) of the diet may be an important tool to monitor the protective effect of plant foods in epidemiological studies. We developed a semi-quantitative FFQ for the assessment of dietary TAC by 3 different assays, i.e., Trolox equivalent antioxidant capacity (TEAC), total radical-trapping antioxidant parameter (TRAP) and ferric reducing-antioxidant power (FRAP). The FFQ consists of 53 questions about the major sources of dietary TAC in Northern Italy and was validated against a 3-d weighed food record (3D-WR) in 285 individuals (159 males and 126 females) aged 35-88 y and living in the province of Parma (Italy). Plasma TAC was also evaluated in a subgroup of subjects using the TEAC and FRAP assays. The FFQ was associated with 3D-WR (quadratic-weighted kappa = 0.49 for TEAC, 0.53 for TRAP, and 0.49 for FRAP; P < 0.0001) and proved reasonably accurate to classify individuals into quartiles of TAC intake. The FFQ had a good repeatability when readministered after 1 y in 55 subjects (quadratic-weighted kappa for intertertile agreement = 0.66 for TEAC, 0.70 for TRAP and 0.68 for FRAP; P < 0.0001). With both dietary instruments, the main contributors to TAC intake were coffee and tea in women and alcoholic beverages in men, followed by fruits and vegetables in both sexes. Plasma TAC and dietary TAC were not associated. In conclusion, our FFQ has the potential for being used to rank subjects on the basis of their antioxidant intake as determined by dietary TAC in large epidemiological studies. The FFQ should be validated in external populations before being used for research purposes.
Authors:
Nicoletta Pellegrini; Sara Salvatore; Silvia Valtueña; Giorgio Bedogni; Marisa Porrini; Valeria Pala; Daniele Del Rio; Sabina Sieri; Cristiana Miglio; Vittorio Krogh; Ivana Zavaroni; Furio Brighenti
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of nutrition     Volume:  137     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-21     Completed Date:  2007-04-10     Revised Date:  2007-06-08    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  93-8     Citation Subset:  IM    
Affiliation:
Department of Public Health, University of Parma, Parma, Italy. nicoletta.pelllegrini@unipr.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Antioxidants / pharmacokinetics*
Body Mass Index
Diet Records*
Food Habits*
Humans
Middle Aged
Questionnaires*
Reproducibility of Results
Chemical
Reg. No./Substance:
0/Antioxidants
Comments/Corrections
Comment In:
J Nutr. 2007 Jun;137(6):1496-7; author reply 1498   [PMID:  17513414 ]
Erratum In:
J Nutr. 2007 Jun;137(6):1499

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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