| Development of spontaneous endometriosis in baboons. | |
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MedLine Citation:
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PMID: 8752259 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the incidence of spontaneous endometriosis over a 32-month period in baboons with initially normal pelves. METHODS: In this observational longitudinal study, which was performed at the Institute of Primate Research, Nairobi (Kenya), 24 baboons with laparoscopically confirmed normal pelves underwent 67 serial laparoscopies (mean 2.8 +/- 1.9, median 3, range 1-6) after 1-3 months (n = 8), 4-6 months (n = 11), 7-9 months (n = 9), 10-12 months (n = 17), 13-15 months (n = 6), 16-18 months (n = 4), 19-21 months (n = 3), 22-24 months (n = 4), 25-27 months (n = 1), and 30-32 months (n = 4). During each laparoscopy, the pelvis was examined for the presence of endometriosis. The number, size, and type of endometriotic implants were noted on a pelvic map, and the endometriosis score and stage were tabulated according to the revised classification of the American Fertility Society. Taking into account the variable length of follow-up, we used life-table analysis to calculate the cumulative incidence of endometriosis. RESULTS: The cumulative incidence of minimal endometriosis (proven by histology) was 64% up to 32 months of follow-up. The eight baboons that developed proven endometriosis were followed over longer periods of time and had undergone more laparoscopies than the animals that did not develop the condition. CONCLUSION: There is a high incidence of minimal endometriosis in baboons, which increases with the time of follow-up and the number of repeat laparoscopies. |
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Authors:
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T M D'Hooghe; C S Bambra; B M Raeymaekers; P R Koninckx |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 88 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1996 Sep |
Date Detail:
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Created Date: 1996-10-17 Completed Date: 1996-10-17 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 462-6 Citation Subset: AIM; IM |
Affiliation:
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Institute of Primate Research, Nairobi, Kenya. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Endometriosis / diagnosis, epidemiology, veterinary* Female Follow-Up Studies Incidence Laparoscopy / veterinary Life Tables Monkey Diseases / diagnosis, epidemiology* Papio* Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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