Document Detail


Development of a sensitive and selective kojic acid sensor based on molecularly imprinted polymer modified electrode in the lab-on-valve system.
MedLine Citation:
PMID:  21962678     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In this work, a kojic acid electrochemical sensor, based on a non-covalent molecularly imprinted polymer (MIP) modified electrode, had been fabricated in the lab-on-valve system. The sensitive layer was synthesized by cyclic voltammetry using o-phenylenediamine as the functional monomer and kojic acid as the template. The template molecules were then removed from the modified electrode surface by washing with NaOH solution. Differential pulse voltammetry method using ferricyanide as probe was applied as the analytical technique, after extraction of kojic acid on the electrode. Chemical and flow parameters associated with the extraction process were investigated. The response recorded with the imprinted sensor exhibited a response in a range of 0.01-0.2μmolL(-1) with a detection limit of 3nmolL(-1). The interference studies showed that the MIP modified electrode had excellent selectivity. Furthermore, the proposed MIP electrode exhibited good sensitivity and low sample/reagent consumption, and the sensor could be applied to the determination kojic acid in cosmetics samples.
Authors:
Yang Wang; Jie Tang; Xiaoyu Luo; Xiaoya Hu; Chun Yang; Qin Xu
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Publication Detail:
Type:  Journal Article     Date:  2011-08-12
Journal Detail:
Title:  Talanta     Volume:  85     ISSN:  1873-3573     ISO Abbreviation:  Talanta     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984816R     Medline TA:  Talanta     Country:  England    
Other Details:
Languages:  eng     Pagination:  2522-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier B.V. All rights reserved.
Affiliation:
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China; The Key Laboratory of Environmental Material and Engineering of Jiangsu Province, Yangzhou University, Yangzhou 225002, China.
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