Document Detail

Development of rib-vertebrae: a new mutation in the house mouse with accessory caudal duplications.
MedLine Citation:
PMID:  4073528     Owner:  NLM     Status:  MEDLINE    
The new recessive mutation rib-vertebrae (rv) causes fusions of lower ribs and malformations of vertebrae, which results from disturbed somite arrangement. In addition, duplications of the caudal neural tube and sometimes unilateral suppression of kidney formation can be observed. The new mutation is compared with the six already known mutations in mice with "Wirbel-Rippen-Syndrome" and with a similar syndrome in man. From the various effects of the rv-gene observed, it is suggested that the gene causes abnormal inner and outer surface formation, producing manifold secondary effects.
K Theiler; D S Varnum
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Anatomy and embryology     Volume:  173     ISSN:  0340-2061     ISO Abbreviation:  Anat. Embryol.     Publication Date:  1985  
Date Detail:
Created Date:  1986-01-23     Completed Date:  1986-01-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7505194     Medline TA:  Anat Embryol (Berl)     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  111-6     Citation Subset:  IM    
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MeSH Terms
Animals, Newborn
Cervical Vertebrae / abnormalities
Crosses, Genetic
Embryo, Mammalian
Genes, Recessive
Gestational Age
Linkage (Genetics)
Lumbar Vertebrae / abnormalities
Mice, Inbred C57BL
Mice, Mutant Strains
Notochord / cytology
Ribs / abnormalities*
Spine / abnormalities*,  embryology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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