Document Detail

Development of a radioimmunoassay for pregnancy-associated plasma protein A and establishment of normal levels in the first trimester of pregnancy.
MedLine Citation:
PMID:  6188409     Owner:  NLM     Status:  MEDLINE    
An accelerated double antibody method has been developed for the radioimmunoassay of pregnancy-associated plasma protein A (PAPP-A) in serum. The workable range for the assay was 0.04-1.8 mg/l of serum. PAPP-A levels were determined in single serum samples from 110 women with prospective normal pregnancies of between 7 and 14 weeks' gestation. The level of pregnancy specific beta 1 glycoprotein (SP1) was also measured in these samples and normal ranges for PAPP-A and SP1 were constructed from the results obtained.
F Anthony; G M Masson; P J Wood
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of clinical biochemistry     Volume:  20 Pt 1     ISSN:  0004-5632     ISO Abbreviation:  Ann. Clin. Biochem.     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0324055     Medline TA:  Ann Clin Biochem     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  26-30     Citation Subset:  IM    
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MeSH Terms
Placenta / physiology
Pregnancy Proteins / analysis*
Pregnancy Trimester, First
Pregnancy-Associated Plasma Protein-A / analysis*
Reference Values
Reg. No./Substance:
0/Pregnancy Proteins; EC 3.4.24.-/Pregnancy-Associated Plasma Protein-A

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