| Development and psychometric evaluation of the German version of the Medication Regimen Complexity Index (MRCI-D). | |
| | |
MedLine Citation:
|
PMID: 21320239 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background Several factors contribute to the complexity of pharmacotherapeutic regimens, like the total number of medications to be taken, the number of dosage units to take at a time, dosage frequency, as well as specific directions concerning the administration. The Medication Regimen Complexity Index (MRCI) is a validated instrument developed in English for the measurement of the complexity of a given pharmacotherapeutic regimen. Objectives Translation of the MRCI into German and evaluation of the translated instrument (MRCI-D) in order to make it more easily accessible for use in German practice and research. Methods The process of validation included the translation of the English version to German, back-translation into English, comparison of the back-translated and the original versions, pre-tests, and pilot-testing of the German version by three raters using 20 medication regimens for inpatients. The subsequent psychometric evaluation included the calculation of inter-rater and test-retest reliability, as well as the assessment of convergent validity. Results The number of medications correlated highly and statistically significantly with the MRCI-D score (0.91, P < 0.001), indicating sufficient convergent validity of the instrument. Both inter-rater and test-retest reliability were very high (intraclass correlation coefficients above 0.80 in all cases). Conclusion Our results demonstrate that the German version of the MRCI reflects the complexity of therapeutic regimens with similar validity and reliability as the established English version. Thus, it may be a valuable tool to analyse therapeutic regimens in both clinical practice and science. |
| | |
Authors:
|
Dorit Stange; Levente Kriston; Claudia Langebrake; Lynda K Cameron; John D Wollacott; Michael Baehr; Dorothee C Dartsch |
Related Documents
:
|
21176319 - Obstetrics and gynaecology as a career choice: a cohort study of canadian medical stude... 12108509 - Ectopic tachycardia originating from the superior vena cava. 8970779 - Prominent pigmented fungiform papillae of the tongue. 21394569 - Role of clinical pharmacists' interventions in detection and prevention of medication e... 21330929 - Patterns of caregiving among patients hospitalized with cardiovascular disease. 12060789 - Seeing is believing? the form and substance of french medical debates over lourdes. 12568259 - Source profiles and ozone formation potentials of volatile organic compounds in three t... 6507609 - Polymorphism of palmar c- and d-line terminations among the sikligars of chandigarh. 12811159 - Professionals must recognize personal responsibility. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-2-14 |
Journal Detail:
|
Title: Journal of evaluation in clinical practice Volume: - ISSN: 1365-2753 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-2-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9609066 Medline TA: J Eval Clin Pract Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 Blackwell Publishing Ltd. |
Affiliation:
|
Pharmacist Head of Pharmacy, Hospital Pharmacy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Scientific Associate and Psychologist, Department of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Pharmacist, Department of Pharmacy and Pharmacology, University of Bath, Bath, UK Pharmacist, Sainsburys Pharmacy, Mansfield, Nottinghamshire, UK Professor, Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Hamburg, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of octreotide on jejunal hypersensitivity triggered by Cryptosporidium parvum intestinal inf...
Next Document: Factors associated with patient and health care system delay in diagnosis and treatment for TB in su...