| Development and pathway formation of peripheral neurons during leech embryogenesis. | |
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MedLine Citation:
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PMID: 9674564 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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By labeling the germinal plates of staged leech embryos with monoclonal antibodies to the immunoglobulin superfamily member Tractin, we have documented the distribution and initial development of peripheral neurons in a hirudinid leech. We find, in addition to sensillar and extrasensillar sensory neurons, that there are 21 identifiable peripheral neurons in each hemisegment. These neurons are found in highly stereotyped positions, and all but two of them are associated with the segmental nerves. We show that eight of the peripheral neurons have the characteristic morphology of stretch receptor neurons and that they form a circumferentially distributed grid aligned in such a way that each of five specialized longitudinal muscle fascicles are monitored by at least two stretch receptor cells covering ventral, lateral, and dorsal regions of the body wall. Furthermore, we show that, in contrast to the dorsal posterior nerve, which is pioneered by central projections, the pathways of the three remaining segmental nerves are likely to be pioneered or guided by peripheral neurons. |
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Authors:
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Y Huang; J Jellies; K M Johansen; J Johansen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of comparative neurology Volume: 397 ISSN: 0021-9967 ISO Abbreviation: J. Comp. Neurol. Publication Date: 1998 Aug |
Date Detail:
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Created Date: 1998-09-24 Completed Date: 1998-09-24 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0406041 Medline TA: J Comp Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 394-402 Citation Subset: IM |
Affiliation:
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Department of Zoology and Genetics, Iowa State University, Ames 50011, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies, Monoclonal / immunology Cell Adhesion Molecules, Neuronal / immunology Embryo, Nonmammalian / physiology Immunohistochemistry / methods Leeches / embryology* Neural Pathways / cytology, embryology Neurons / physiology* Peripheral Nerves / cytology, embryology* |
| Grant Support | |
ID/Acronym/Agency:
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NS 28857/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Cell Adhesion Molecules, Neuronal; 0/tractin protein, Hirudo medicinalis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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