Document Detail

Development of a novel temporary epicardial pacing wire with biodegradable film.
MedLine Citation:
PMID:  16996959     Owner:  NLM     Status:  MEDLINE    
PURPOSE: A temporary epicardial pacing wire (TEPW) has been routinely placed in patients undergoing cardiac surgery. However, its fixation or removal occasionally causes troublesome complications. The aim of this study is to develop a novel TEPW using biodegradable film to fix the electrode to the epicardium without needle stabbing. DESCRIPTION: A biodegradable film was prepared with poly(L-lactide-co-epsilon-caprolactone). The film has a honeycomb-patterned structure that serves as a temporary adhesive for the myocardial surface, and the electrode was incorporated within the film. The novel TEPW was placed on the ventricular epicardium of dogs (group A, n = 5). As a control, conventional TEPW was inserted (group B, n = 6). The pacing threshold, R wave amplitude, impedance, and slew rate were measured at postoperative days 0, 1, 3, 5, 7, and 14, and complications after removal were checked. EVALUATION: All measurements in both groups were identified and differences were not observed. In addition, the novel TEPWs could be easily removed without related complications. CONCLUSIONS: This novel TEPW is safe and feasible for postoperative management of cardiac surgeries.
Yuji Narita; Yukako Fukuhira; Hideaki Kagami; Eiichi Kitazono; Hiroaki Kaneko; Yoshihiko Sumi; Akihiko Usui; Minoru Ueda; Yuichi Ueda
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  82     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-25     Completed Date:  2006-10-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1489-93     Citation Subset:  AIM; IM    
Department of Tissue Engineering, Nagoya University School of Medicine, Nagoya, Japan.
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MeSH Terms
Absorbable Implants*
Arrhythmias, Cardiac / etiology,  therapy*
Cardiac Pacing, Artificial
Cardiac Surgical Procedures / adverse effects
Coated Materials, Biocompatible / therapeutic use
Electrodes, Implanted
Equipment Design
Hexanoic Acids / therapeutic use
Lactones / therapeutic use
Pacemaker, Artificial*
Polyesters / therapeutic use
Suture Techniques
Tissue Adhesives / therapeutic use*
Reg. No./Substance:
0/Coated Materials, Biocompatible; 0/Hexanoic Acids; 0/Lactones; 0/Polyesters; 0/Tissue Adhesives; 26969-66-4/poly(lactide); 502-44-3/caprolactone
Comment In:
Ann Thorac Surg. 2006 Oct;82(4):1493   [PMID:  16996960 ]

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