Document Detail

Development of a novel method for operating magnetic particles, Magtration Technology, and its use for automating nucleic acid purification.
MedLine Citation:
PMID:  16233029     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Magnetic particles are useful for simple and efficient nucleic acid extraction. To achieve fully automated nucleic acid extraction and purification using magnetic particles, a new method for operating magnetic particles, Magtration Technology, was developed. In this method, magnetic separation is performed in a specially designed disposable tip. This enables high recovery of magnetic particles with high reproducibility. The features of this technology are (i) a simple mechanism for process control and (ii) flexible software to enable adaptation to commercially available reagents. Automated instruments based on Magtration Technology were developed and used for nucleic acid extraction. Total DNA, total RNA and plasmids were purified by Magtration Technology at an efficiency comparable to that of manual methods.
K Obata; O Segawa; M Yakabe; Y Ishida; T Kuroita; K Ikeda; B Kawakami; Y Kawamura; M Yohda; T Matsunaga; H Tajima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bioscience and bioengineering     Volume:  91     ISSN:  1389-1723     ISO Abbreviation:  J. Biosci. Bioeng.     Publication Date:  2001  
Date Detail:
Created Date:  2005-10-19     Completed Date:  2005-11-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888800     Medline TA:  J Biosci Bioeng     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  500-3     Citation Subset:  -    
Precision System Science Co. Ltd., 88 Kamihongo, Matsudo, Chiba 271-0064, Japan.
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