Document Detail

Development of nonexercise prediction models of maximal oxygen uptake in healthy Japanese young men.
MedLine Citation:
PMID:  17115179     Owner:  NLM     Status:  MEDLINE    
The present study developed nonexercise models for predicting maximal oxygen uptake (VO2max) using skeletal muscle (SM) mass and cardiac dimensions and to investigate the validity of these equations in healthy Japanese young men. Sixty healthy Japanese men were randomly separated into two groups: 40 in the development group and 20 in the validation group. VO2max during treadmill running was measured using an automated breath-by-breath mass spectrometry system. Left ventricular internal dimensions at end-diastole (LVIDD) and at end-systole (LVIDS) were measured using M-mode ultrasound with a 2.5 MHz transducer. Stroke volume (SV) was calculated based on the Pombo rule. SM mass was predicted by B-mode ultrasound muscle thickness. Correlations were observed between VO2max and predicted thigh (r = 0.74, P < 0.001) and lower leg SM mass (r = 0.55, P < 0.001). Furthermore, there were correlations between VO2max and LVIDD (r = 0.74, P < 0.001) and SV (r = 0.72, P < 0.001). Stepwise regression analysis was applied to thigh SM mass and SV for prediction of VO2max in the development group, and these parameters were closely correlated with absolute measured VO2max (R2 = 0.72, P < 0.001) by multiple regression analysis. When the VO2max prediction equations were applied to the validation group, significant correlations were also observed between the measured and predicted VO2max (R2 = 0.83, P < 0.001). These results suggested that nonexercise prediction of VO2max using thigh SM mass and cardiac dimension is a valid method to predict VO2max in young Japanese adults.
Kiyoshi Sanada; Taishi Midorikawa; Tomohiro Yasuda; Charles F Kearns; Takashi Abe
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Validation Studies     Date:  2006-11-07
Journal Detail:
Title:  European journal of applied physiology     Volume:  99     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-25     Completed Date:  2007-04-20     Revised Date:  2007-11-21    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  143-8     Citation Subset:  IM    
Consolidated Research Institute for Advanced Science and Medical Care, Waseda University, 513 Wasedatsurumaki-cho, Shinjuku-ku, Tokyo, 162-0041, Japan.
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MeSH Terms
Asian Continental Ancestry Group*
Exercise Test
Heart / anatomy & histology*,  physiology
Heart Ventricles / anatomy & histology,  ultrasonography
Models, Biological*
Muscle, Skeletal / anatomy & histology*,  ultrasonography
Organ Size
Oxygen Consumption*
Predictive Value of Tests
Reference Values
Reproducibility of Results
Stroke Volume
Comment In:
Eur J Appl Physiol. 2007 Sep;101(2):263-4; author reply 265-6   [PMID:  17520270 ]

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