Document Detail

Development and multiplexed control of latching pneumatic valves using microfluidic logical structures.
MedLine Citation:
PMID:  16652177     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Novel latching microfluidic valve structures are developed, characterized, and controlled independently using an on-chip pneumatic demultiplexer. These structures are based on pneumatic monolithic membrane valves and depend upon their normally-closed nature. Latching valves consisting of both three- and four-valve circuits are demonstrated. Vacuum or pressure pulses as short as 120 ms are adequate to hold these latching valves open or closed for several minutes. In addition, an on-chip demultiplexer is demonstrated that requires only n pneumatic inputs to control 2(n-1) independent latching valves. These structures can reduce the size, power consumption, and cost of microfluidic analysis devices by decreasing the number of off-chip controllers. Since these valve assemblies can form the standard logic gates familiar in electronic circuit design, they should be useful in developing complex pneumatic circuits.
William H Grover; Robin H C Ivester; Erik C Jensen; Richard A Mathies
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Publication Detail:
Type:  Journal Article     Date:  2006-04-06
Journal Detail:
Title:  Lab on a chip     Volume:  6     ISSN:  1473-0197     ISO Abbreviation:  Lab Chip     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-02     Completed Date:  2007-05-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128948     Medline TA:  Lab Chip     Country:  England    
Other Details:
Languages:  eng     Pagination:  623-31     Citation Subset:  -    
Department of Chemistry, University of California, Berkeley, CA 94720, USA.
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