| Development of the mammalian female reproductive tract. | |
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MedLine Citation:
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PMID: 16002989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The female reproductive tract (FRT), which includes the oviduct, uterus, cervix and vagina, is critical for mammalian reproduction. Recent research using knockout mice has contributed substantially to our understanding of the molecular mechanisms governing FRT development. Aside from satisfying our curiosities about the origin of life, these studies have provided us with a better understanding of FRT disorders and ways to improve female fertility. Here we review genes that are involved in various stages of sexual duct formation and development in mammals. In addition, the effect of exogenous estrogen such as DES on FRT development is also discussed. |
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Authors:
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Yan Yin; Liang Ma |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of biochemistry Volume: 137 ISSN: 0021-924X ISO Abbreviation: J. Biochem. Publication Date: 2005 Jun |
Date Detail:
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Created Date: 2005-07-08 Completed Date: 2005-09-16 Revised Date: 2007-12-19 |
Medline Journal Info:
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Nlm Unique ID: 0376600 Medline TA: J Biochem Country: Japan |
Other Details:
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Languages: eng Pagination: 677-83 Citation Subset: IM |
Affiliation:
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Division of Dermatology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Patterning Cell Differentiation Diethylstilbestrol / adverse effects Female Gene Expression Regulation, Developmental* Genes, Homeobox* Genitalia, Female / embryology* Male Mice Mice, Knockout Mullerian Ducts / embryology Uterus / embryology |
| Chemical | |
Reg. No./Substance:
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56-53-1/Diethylstilbestrol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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