Document Detail

Development of an intravascular lung assist device.
MedLine Citation:
PMID:  2597558     Owner:  NLM     Status:  MEDLINE    
Intravascular lung assist devices (ILADs) must provide sufficient gas transport without excessive pressure drop. In vitro studies of fiber-bundle devices determined the effect of geometric configuration on gas transfer efficiency, the amount of surface area needed to achieve sufficient gas transport, and the relationship between gas transport and blood-side pressure drop. ILADs with cross-flow fibers transfer at least 10 times more O2 than parallel flow ILADs of the same surface area, and six to eight times more CO2. Some tested devices with 0.4-0.6 m2 of surface area can transfer 100 ml/min of both O2 and CO2. Configurations with high gas transport, however, often require moderate pressure drops.
S N Vaslef; L F Mockros; R W Anderson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  ASAIO transactions / American Society for Artificial Internal Organs     Volume:  35     ISSN:  0889-7190     ISO Abbreviation:  ASAIO Trans     Publication Date:    1989 Jul-Sep
Date Detail:
Created Date:  1990-02-06     Completed Date:  1990-02-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8611947     Medline TA:  ASAIO Trans     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  660-4     Citation Subset:  IM    
Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208.
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MeSH Terms
Equipment Design
Membranes, Artificial
Models, Cardiovascular
Oxygen / blood
Oxygenators, Membrane*
Pulmonary Gas Exchange / physiology*
Reg. No./Substance:
0/Membranes, Artificial; 7782-44-7/Oxygen

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