Document Detail

Development of intestinal microbiota in infants and its impact on health.
MedLine Citation:
PMID:  23332725     Owner:  NLM     Status:  Publisher    
Throughout the human lifetime, the intestinal microbiota performs vital functions, such as barrier function, metabolic reactions, trophic effects, and maturation of the host's innate and adaptive immune responses. Development of the intestinal microbiota in infants is characterized by rapid and large changes in microbial abundance, diversity, and composition. These changes are influenced by medical, cultural, and environmental factors such as mode of delivery, diet, familial environment, diseases, and therapies used. Thus, it is nearly impossible to define a universal standard for intestinal colonization and development of the intestinal microbiota. This review discusses recent data on the early colonization of the gut by microbial species, development of the intestinal microbiota, and its impact on health.
Sebastien Matamoros; Christele Gras-Leguen; Françoise Le Vacon; Gilles Potel; Marie-France de La Cochetiere
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-14
Journal Detail:
Title:  Trends in microbiology     Volume:  -     ISSN:  1878-4380     ISO Abbreviation:  Trends Microbiol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9310916     Medline TA:  Trends Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Institut des Nutraceutiques et des Aliments Fonctionnels (INAF), Université Laval, 2440, Boul. Hochelaga, Quebec G1V 0A6, Canada.
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