Document Detail


Development of an improved target for [18F]F2 production.
MedLine Citation:
PMID:  7711684     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An A1 body target with improved yields of electrophilic [18F]F2 on the Siemens/CTI 11 MeV proton cyclotron at Wisconsin has been developed. The saturation yield is 3.10 +/- 0.40 GBq/microA for beam currents up to 45 microA. The target has routinely produced 20-40 GBq of [18F]F2 for clinical and experimental use over 1600 microA-h operation, with a maximum yield to date of 45.5 GBq (1.2 Ci). Target design, performance and reliability are discussed.
Authors:
A D Roberts; T R Oakes; R J Nickles
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine     Volume:  46     ISSN:  0969-8043     ISO Abbreviation:  Appl Radiat Isot     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-05-18     Completed Date:  1995-05-18     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9306253     Medline TA:  Appl Radiat Isot     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  87-91     Citation Subset:  IM    
Affiliation:
Department of Medical Physics, 1530 Medical Sciences Center, Madison, WI 53706-1532.
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MeSH Terms
Descriptor/Qualifier:
Aluminum
Cyclotrons / instrumentation*
Dihydroxyphenylalanine / analogs & derivatives,  chemical synthesis
Fluorine Radioisotopes / isolation & purification*
Methods
Nickel
Grant Support
ID/Acronym/Agency:
5-T32 CA 09206-16/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Fluorine Radioisotopes; 63-84-3/Dihydroxyphenylalanine; 7429-90-5/Aluminum; 7440-02-0/Nickel; 75290-51-6/fluorodopa F 18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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