Document Detail

Development and implementation of a pharmacist-managed inpatient warfarin protocol.
MedLine Citation:
PMID:  16252031     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Because of the complexities of warfarin administration and its bleeding complications, a pharmacist-managed protocol for warfarin administration was developed at Baylor University Medical Center. The protocol incorporated current clinical guidelines and evidence-based medicine. Clinical outcomes under the protocol were compared with those of usual care, physician management, in a pilot study. Twenty-nine patients were enrolled in the protocol group and 22 in the control group between August 2004 and November 2004. Results showed that patients in both groups achieved therapeutic ranges of warfarin within 6 days. However, the pharmacist-managed patients exhibited a trend toward fewer adverse drug reactions (7% vs 14%) and fewer supratherapeutic international normalized ratios (17% vs 27%) than the control group, although the difference was not statistically significant. Based on these results and the results of similar larger studies showing the effectiveness of pharmacist-managed warfarin administration, Baylor University Medical Center made the protocol available for use in the hospital in May 2005.
David L Damaske; Robert W Baird
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Proceedings (Baylor University. Medical Center)     Volume:  18     ISSN:  0899-8280     ISO Abbreviation:  Proc (Bayl Univ Med Cent)     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-27     Completed Date:  2005-11-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9302033     Medline TA:  Proc (Bayl Univ Med Cent)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  397-400     Citation Subset:  -    
Department of Pharmacy Services, Baylor University Medical Center, Dallas, Texas 75246, USA.
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